As Christ passes by, the two blind men have the ultimate opportunity, and they take advantage of it. He did not pass by every day. If the two men had not pursued Him for healing at once, they may never have had another opportunity to be healed. Spiritually, the same is true for everyone. God opens doors of opportunity for salvation and service, but very few take Him up on it: "For many are called but few are chosen" (Matthew 22:14). A person must pass through those doors quickly, or they will close and the opportunity will be forever squandered (Matthew 25:6-12; Revelation 3:20). A Christian may also miss rendering service to others because he fails to take advantage of opportunities. With opportunities come blessings, and if an opportunity is missed, so are the blessings.
If we want blessings from Christ, we must follow Him. The blind men desired physical sight and so followed Him. Those who are indifferent in their faithfulness to Christ will have trouble receiving any blessing from Him, for He treats His followers differently from those who do not follow Him. At times, even a church member will complain of a lack of God's blessings in his life, but it may be that he has not followed Christ diligently and recognized the abundance of spiritual blessings he has received. God even goes so far as to warn His ministers that, if we fail to take to heart His warning about due diligence in serving Him with integrity, He will curse us (Malachi 2:1-2).
Christ calls, "Follow Me!" (Matthew 4:19; 8:22; Luke 18:22), but following is not easy because, "Whoever desires to come after Me, let him deny himself, and take up his cross, and follow Me" (Mark 8:34).