Nowhere does Matthew—or anyone else—ever tell us that God acquiesced to carry out vengeance on those who cried, "Crucify Him!" before Pilate's judgment hall. Nowhere does Matthew intimate that God consented to punish their children over the centuries. If He had committed Himself to carry out these peoples' so-called "curse," He would have knowingly bound Himself to violate His own law for centuries.
Why, then, have the Jews found themselves so often in such dire straits over the years, not only after the crucifixion of Christ, but for centuries before? They have been persecuted by the Egyptians, the Philistines, the Edomites, the Canaanites, the Sidonians, the Hivites, the Moabites (see Judges 3:3-12), and the Midianites (see Judges 8:1). The catalog of their tormentors includes the Persians of Haman's time, the Greeks of Antiochus' time, the Romans of Imperial times, and afterwards various European and Muslim peoples to the present. Their history of persecution would fill volumes.
Anciently, only the Jews, along with their Israelite brethren, were the recipients of God's revelation: "You only have I known of all the families of the earth" (Amos 3:2). God counts that revelation as a precious blessing to the family of Abraham, as Paul writes in Romans 3:1-2: "What advantage then has the Jew, or what is the profit of circumcision? Much in every way! Chiefly because to them were committed the oracles of God."
To Paul, the Jews were not cursed, but were first, the Greeks second (Romans 2:9-10). He took seriously his commission to carry God's name "before . . . the children of Israel" (Acts 9:15). The book of Acts records that in every town and city he visited, he went first to the local Jewish synagogue; after that, he preached the gospel to the Gentiles. Indeed, he admonished the church at Thessalonica to "become imitators of the churches of God which are in Judea . . . " (I Thessalonians 2:14).
God gave the Jews a lot. Here, the principle of Luke 12:48 enters the picture: "For everyone to whom much is given, from him much will be required; and to whom much has been committed, of him they will ask the more."
As we know from the Old Testament and as history since has demonstrated, the Jews have repeatedly rejected God, treading His oracles underfoot. Today, many are the Jews who have forsaken God and joined the vanguard of liberal secularism (read, atheism) in the arts, law, politics, science, education—in virtually every field of human endeavor. Throughout their history, many Jews have scorned God's revelation, purposefully making themselves a profane people. So, the corollary of Christ's principle applies, as stated in Luke 12:47: "And that servant who knew his master's will, and did not prepare himself or do according to his will, shall be beaten with many stripes."
The Jews, more than any single people in history, knew God's will, as it is expressed in the "oracles"—His revelation to them. They often have rejected it. As often as they do, their apostasy has carried with it the penalty of "many stripes."