Our Savior is trying to explain the relative values of our physical lives and what we can humanly accomplish to what awaits us in what is commonly called the afterlife. In short, there is no comparison!
Notice the Bible's consistency on the value of human life apart from God:
» Ecclesiastes 1:2-4: "Vanity of vanities, all is vanity." What profit has a man from all his labor in which he toils under the sun? One generation passes away, and another generation comes; but the earth abides forever.
» Job 14:1-2: Man who is born of woman is of few days and full of trouble. He comes forth like a flower and fades away; he flees like a shadow and does not continue.
» Psalm 90:10: The days of our lives are seventy years; and if by reason of strength they are eighty years, yet their boast is only labor and sorrow; for it is soon cut off, and we fly away.
» Isaiah 40:6-8: All flesh is grass, and all its loveliness is like the flower of the field. The grass withers, the flower fades, because the breath of the Lord blows upon it; surely the people are grass. The grass withers, the flower fades, but the word of our God stands forever.
» James 4:14: For what is your life? It is even a vapor that appears for a little time and then vanishes away.
» I John 2:17: And the world is passing away, and the lust of it; but he who does the will of God abides forever.
The physical life we would live now is a bowl of lentils compared with eternal life. It is nothing more than a vapor, a breath, a shadow. The passing pleasures and cares of the world will only gratify and satisfy the immediate desires. If our only interest is the immediate gratification that the world has to offer, we are indeed saying, "What profit is the Kingdom of God to me now?" Like Esau, we will despise our inheritance and go our way apart from God.
Our inheritance is the Kingdom of God. By seeking it and His righteousness first (Matthew 6:33), we are telling God that we place high value on it, that we want it, that we want to be like Him and think like Him, and that we can be trusted to take care of His estate and to live and reign with Christ.