Paul instructs us not only not to neglect prayer, but also to keep at it in earnest. He advises us to watch for opportunities to pray for others and for situations, especially in the church, that require prayer. This important work belongs to us individually.
At the time, the apostle was imprisoned in Rome, and he desperately longed to be released so that he could proclaim the gospel and teach God's way as he had been commissioned to do. He was certain that, through the power of prayer, God would open a door - perhaps the door to his prison - to present God's Word to others. The apostle knew that this was God's will for him, so prayer according to that same will would be effective.
The lesson for us today is to pray for the ministers who speak to us, teaching the doctrines and principles that will help us to overcome, grow in grace and knowledge, and obtain the understanding to put on the image of Christ. We must realize that their messages go out, not just to us, but to other members of the congregation who may have different needs than we do. In addition, they are spread around the world via the Internet to people who may have had a long association with God's truth, as well as to those who are truly babes in the Word of God. We need to pray that God inspires the ministry to fill the needs that He sees in today's very diverse audience.
Prior to each Sabbath service, we should humbly pray in deep appreciation for whoever is presenting the messages, asking that God would guide their messages and that all who hear them might receive what Jesus Christ wants them to understand. Such an attitude and prayer will please God greatly.